TB-Profiler result

Run: ERR11068487
Summary

Run ID: ERR11068487

Sample name:

Date: 06-04-2023 14:36:11

Number of reads: 3318861

Percentage reads mapped: 99.31

Strain: lineage4.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.1 Euro-American (TUR) H3;H4 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576455 p.Val370Met missense_variant 0.18
mshA 576693 p.Asn449Ser missense_variant 0.15
ccsA 620041 p.Ala51Thr missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155371 c.741C>T synonymous_variant 1.0
PPE35 2169879 p.Phe245Cys missense_variant 1.0
PPE35 2170121 c.492G>A synonymous_variant 0.2
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714979 c.354G>A synonymous_variant 1.0
ribD 2987310 p.Gly158Ser missense_variant 0.33
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339304 c.192delC frameshift_variant 0.22
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568420 p.Arg87Pro missense_variant 0.33
whiB7 3568428 c.252A>G synonymous_variant 0.33
fbiB 3642159 c.625C>T synonymous_variant 0.1
rpoA 3878590 c.-83G>C upstream_gene_variant 0.33
embC 4240476 p.Ala205Val missense_variant 0.11
embC 4242551 p.Arg897Trp missense_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244909 c.1677C>T synonymous_variant 0.11
embB 4247152 c.639G>A synonymous_variant 0.11
embB 4247641 c.1128G>T synonymous_variant 0.14
embB 4249594 c.3081G>A synonymous_variant 1.0
aftB 4267673 p.Trp388Cys missense_variant 0.2
ethA 4328376 c.-903G>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0