TB-Profiler result

Run: ERR11068688
Summary

Run ID: ERR11068688

Sample name:

Date: 06-04-2023 22:10:32

Number of reads: 4079570

Percentage reads mapped: 99.79

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 766969 c.3600C>T synonymous_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416976 c.372C>T synonymous_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471786 n.-60T>G upstream_gene_variant 0.17
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rpsA 1834744 c.1203C>T synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918118 p.Arg60His missense_variant 0.12
PPE35 2168149 p.Pro822Ser missense_variant 1.0
PPE35 2170422 p.Ala64Val missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyX 3067235 c.711C>T synonymous_variant 0.14
thyX 3067497 p.Leu150Arg missense_variant 0.11
thyX 3067944 p.Val1Gly missense_variant 0.12
whiB7 3568420 p.Arg87Pro missense_variant 0.33
whiB7 3568425 c.255T>G synonymous_variant 0.2
fbiB 3642242 c.708C>A synonymous_variant 0.12
rpoA 3878641 c.-134C>G upstream_gene_variant 0.21
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243586 p.Phe118Leu missense_variant 0.17
embA 4244515 p.Ala428Gly missense_variant 0.12
embA 4244871 p.Gly547Ser missense_variant 1.0
aftB 4268435 c.402C>T synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0