TB-Profiler result

Run: ERR11068771
Summary

Run ID: ERR11068771

Sample name:

Date: 07-04-2023 01:14:49

Number of reads: 3259941

Percentage reads mapped: 99.47

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575371 c.24C>T synonymous_variant 0.12
mshA 575679 p.Asn111Ser missense_variant 1.0
mshA 576113 p.Arg256Gly missense_variant 0.57
mshA 576116 p.Ala257Pro missense_variant 0.3
mshA 576119 p.Ala258Pro missense_variant 0.27
ccsA 619831 c.-60T>C upstream_gene_variant 0.25
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304256 c.1326G>A synonymous_variant 0.12
Rv1258c 1407053 c.288C>T synonymous_variant 0.12
Rv1258c 1407148 p.Ala65Thr missense_variant 0.11
Rv1258c 1407149 c.192C>T synonymous_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918066 p.Ala43Pro missense_variant 0.22
PPE35 2170138 p.Ser159Pro missense_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
kasA 2518693 c.579C>T synonymous_variant 0.12
eis 2715569 c.-237C>T upstream_gene_variant 0.29
folC 2746675 c.924C>A synonymous_variant 0.25
pepQ 2860146 c.273C>T synonymous_variant 0.5
thyX 3067971 c.-26T>C upstream_gene_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339733 p.Ala206Thr missense_variant 0.4
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3642033 p.Ala167Thr missense_variant 0.17
rpoA 3878559 c.-53delC upstream_gene_variant 0.33
clpC1 4040256 p.Ala150Val missense_variant 0.12
embC 4242470 p.Arg870Trp missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243523 c.291C>A synonymous_variant 0.17
embB 4248605 c.2092C>T synonymous_variant 0.12
aftB 4268333 c.504C>T synonymous_variant 0.11
ethR 4328030 p.Ala161Gly missense_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0