TB-Profiler result

Run: ERR11068795

Summary

Run ID: ERR11068795

Sample name:

Date: 07-04-2023 02:05:29

Number of reads: 3266284

Percentage reads mapped: 99.37

Strain: lineage4.2.2.1

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2.1 Euro-American LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576077 c.730C>T synonymous_variant 1.0
mshA 576116 p.Ala257Pro missense_variant 0.4
mshA 576119 p.Ala258Pro missense_variant 0.47
mshA 576616 c.1269G>A synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304320 p.Ser464Gly missense_variant 0.1
Rv1258c 1407533 c.-193G>C upstream_gene_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918066 p.Ala43Pro missense_variant 0.33
katG 2155730 c.382C>A synonymous_variant 0.14
Rv1979c 2221905 c.1260T>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746572 p.Arg343Cys missense_variant 0.12
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339653 p.Thr179Lys missense_variant 0.12
fbiD 3339758 p.Arg214Leu missense_variant 0.13
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568420 p.Arg87Pro missense_variant 0.38
whiB7 3568428 c.252A>G synonymous_variant 0.25
rpoA 3878641 c.-134C>G upstream_gene_variant 0.26
embC 4241673 p.Ala604Val missense_variant 0.2
embC 4241732 p.Ala624Pro missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244589 c.1357C>T synonymous_variant 0.2
embB 4246547 p.Pro12Thr missense_variant 0.12
embB 4247030 p.Arg173Cys missense_variant 0.22
ethR 4328030 p.Ala161Gly missense_variant 0.31
ethR 4328039 p.Arg164Pro missense_variant 0.24
whiB6 4338595 c.-75delG upstream_gene_variant 1.0