TB-Profiler result

Run: ERR11068816
Summary

Run ID: ERR11068816

Sample name:

Date: 07-04-2023 02:53:20

Number of reads: 4049864

Percentage reads mapped: 99.36

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9068 c.1767G>T synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491326 p.Ala182Thr missense_variant 0.2
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305455 p.Arg842His missense_variant 0.14
Rv1258c 1407182 c.159G>A synonymous_variant 0.17
embR 1416960 p.Arg130Trp missense_variant 0.17
embR 1417009 c.339G>C synonymous_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674793 p.Ala198Thr missense_variant 0.11
inhA 1674818 p.Ala206Val missense_variant 0.67
inhA 1674886 p.Gly229Ser missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170513 c.100C>T synonymous_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289919 c.-678C>T upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
eis 2714766 c.567G>A synonymous_variant 0.13
eis 2714970 c.363C>T synonymous_variant 0.14
folC 2747335 c.264G>A synonymous_variant 0.25
folC 2747341 c.258C>T synonymous_variant 0.18
pepQ 2860072 p.Gly116Asp missense_variant 0.14
thyX 3067313 c.633G>C synonymous_variant 0.2
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339358 p.Ala81Thr missense_variant 0.11
Rv3083 3449051 p.Ile183Thr missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3641969 c.435C>A synonymous_variant 0.5
fbiB 3642793 p.Pro420Arg missense_variant 0.11
rpoA 3878641 c.-134C>G upstream_gene_variant 0.24
clpC1 4040060 c.645C>A synonymous_variant 0.12
clpC1 4040235 p.Gly157Ala missense_variant 0.4
embC 4240485 p.Ala208Val missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243496 c.264G>A synonymous_variant 0.1
embA 4244611 p.Ala460Val missense_variant 0.22
embB 4246999 c.486C>T synonymous_variant 0.12
ethA 4326026 p.Arg483Thr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0