TB-Profiler result

Run: ERR11068824
Summary

Run ID: ERR11068824

Sample name:

Date: 07-04-2023 03:13:16

Number of reads: 4035632

Percentage reads mapped: 99.81

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.25
mshA 576116 p.Ala257Pro missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777330 c.1150delG frameshift_variant 0.2
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1407080 c.261C>T synonymous_variant 0.25
Rv1258c 1407123 p.Arg73Gln missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
PPE35 2170354 p.Ala87Thr missense_variant 0.17
Rv1979c 2222826 c.338delT frameshift_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747727 c.-129C>T upstream_gene_variant 0.17
thyX 3067481 c.465C>A synonymous_variant 0.11
thyX 3067934 c.12C>T synonymous_variant 0.1
ald 3087326 c.507C>A synonymous_variant 0.18
fbiD 3339752 p.Ala212Val missense_variant 0.22
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
clpC1 4038742 p.Val655Met missense_variant 0.99
clpC1 4040235 p.Gly157Ala missense_variant 0.24
embC 4242627 p.Ala922Val missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247888 p.Gly459Ser missense_variant 0.18
ethA 4328443 c.-970C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0