TB-Profiler result

Run: ERR11068836
Summary

Run ID: ERR11068836

Sample name:

Date: 07-04-2023 03:47:44

Number of reads: 3645820

Percentage reads mapped: 99.73

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491222 p.Arg147His missense_variant 1.0
ccsA 620130 c.240G>A synonymous_variant 0.12
rpoB 760474 p.Lys223Thr missense_variant 0.17
rpoC 763868 p.Asp167Asn missense_variant 1.0
rpoC 764554 c.1185C>T synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304424 c.1494C>G synonymous_variant 0.17
embR 1416968 p.Ala127Val missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475778 n.2121G>T non_coding_transcript_exon_variant 0.67
rpsA 1834860 p.Ala440Val missense_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1917973 p.Val12Leu missense_variant 0.22
PPE35 2168149 p.Pro822Ser missense_variant 1.0
PPE35 2170432 p.Ser61Pro missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715006 c.327C>G synonymous_variant 0.11
folC 2746337 p.Ala421Val missense_variant 1.0
pepQ 2860128 c.291C>T synonymous_variant 0.15
thyX 3067262 c.684C>T synonymous_variant 0.17
thyX 3067321 p.Arg209Trp missense_variant 0.17
thyA 3074496 c.-25C>T upstream_gene_variant 0.13
ald 3087608 c.789A>C synonymous_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3083 3448500 c.-4A>G upstream_gene_variant 1.0
Rv3083 3448501 c.-3G>T upstream_gene_variant 1.0
fprA 3473864 c.-143G>A upstream_gene_variant 1.0
fbiA 3641254 p.Ala238Thr missense_variant 0.12
fbiB 3641961 p.Thr143Pro missense_variant 0.17
clpC1 4039199 c.1506C>A synonymous_variant 1.0
embC 4242549 p.Val896Asp missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246544 p.Thr11Pro missense_variant 0.12
embB 4247871 p.Ala453Val missense_variant 0.12
embB 4248555 p.Gly681Ala missense_variant 0.11
ethR 4328002 p.Val152Met missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408466 c.-264C>T upstream_gene_variant 0.17
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0