TB-Profiler result

Run: ERR11081537
Summary

Run ID: ERR11081537

Sample name:

Date: 09-04-2023 01:56:01

Number of reads: 1218335

Percentage reads mapped: 99.5

Strain: lineage4.2.2.2

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 0.98
lineage4.2.2 Euro-American (Ural) T;LAM7-TUR None 0.96
lineage4.2.2.2 Euro-American (Ural) T;LAM7-TUR None 0.95
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6122 p.Ala295Thr missense_variant 0.17
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8688 p.Ala463Ser missense_variant 0.92
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575455 c.108G>T synonymous_variant 0.14
mshA 576077 c.730C>T synonymous_variant 0.94
mshA 576108 p.Ala254Gly missense_variant 0.15
mshA 576448 c.1101A>C synonymous_variant 0.19
mshA 576489 p.Val381Gly missense_variant 0.25
ccsA 620839 c.949C>T synonymous_variant 0.12
rpoC 763031 c.-339T>C upstream_gene_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417141 c.207C>A synonymous_variant 0.11
atpE 1461172 p.Pro43Leu missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475959 n.2302C>T non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.18
folC 2747104 p.Asp165Glu missense_variant 0.92
pepQ 2860159 p.Ala87Gly missense_variant 0.27
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 0.98
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.33
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878597 c.-90G>C upstream_gene_variant 0.43
rpoA 3878613 c.-106A>C upstream_gene_variant 0.4
rpoA 3878626 c.-119A>C upstream_gene_variant 0.29
rpoA 3878637 c.-130G>C upstream_gene_variant 0.33
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.29
ethA 4328212 c.-740delC upstream_gene_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0