TB-Profiler result

Run: ERR1200621
Summary

Run ID: ERR1200621

Sample name:

Date: 27-03-2023 13:27:34

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.6

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7493 c.192C>T synonymous_variant 0.23
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7799 c.498A>C synonymous_variant 0.2
gyrA 8377 p.Asp359Gly missense_variant 0.22
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575309 c.-39C>G upstream_gene_variant 0.23
rpoC 762836 c.-534C>G upstream_gene_variant 0.27
rpoC 764725 p.Phe452Leu missense_variant 0.2
rpoC 764751 p.Val461Gly missense_variant 0.3
rpoC 766584 p.Gly1072Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406750 c.591C>A synonymous_variant 0.16
rrs 1471658 n.-188T>G upstream_gene_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473343 n.1498G>T non_coding_transcript_exon_variant 0.12
rrl 1474380 n.723G>T non_coding_transcript_exon_variant 0.16
rrl 1476408 n.2751G>C non_coding_transcript_exon_variant 0.13
fabG1 1673449 p.Thr4Pro missense_variant 0.28
inhA 1674892 p.Asn231Asp missense_variant 0.24
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918069 p.Thr44Pro missense_variant 0.32
ndh 2102891 p.Phe51Ser missense_variant 0.2
PPE35 2167871 c.2742G>C synonymous_variant 0.22
PPE35 2170156 p.Ala153Pro missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714366 p.Val323Leu missense_variant 0.19
ahpC 2725954 c.-239C>T upstream_gene_variant 0.24
ahpC 2726550 p.Gln120Lys missense_variant 0.21
ahpC 2726756 c.564C>G synonymous_variant 0.22
folC 2746186 c.1413G>C synonymous_variant 0.14
folC 2746910 p.Thr230Ser missense_variant 1.0
folC 2747218 p.Ile127Met missense_variant 0.16
ribD 2987392 p.Arg185Pro missense_variant 0.23
Rv2752c 3064552 p.Arg547Pro missense_variant 0.14
Rv2752c 3064741 p.Gly484Ala missense_variant 0.18
Rv2752c 3065265 c.927C>G synonymous_variant 0.21
Rv3083 3449058 p.Ser185Arg missense_variant 0.27
Rv3083 3449673 p.Tyr390* stop_gained 0.2
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474601 p.Arg199Gly missense_variant 0.13
fprA 3475280 p.Val425Gly missense_variant 0.32
Rv3236c 3612835 c.282T>G synonymous_variant 0.23
fbiB 3641955 p.Gly141Arg missense_variant 0.21
alr 3840268 p.Thr385Pro missense_variant 0.18
alr 3841504 c.-84C>G upstream_gene_variant 0.12
rpoA 3877766 p.Ala248Pro missense_variant 0.18
rpoA 3878641 c.-135delG upstream_gene_variant 1.0
clpC1 4039363 p.Ala448Pro missense_variant 0.22
clpC1 4039932 p.Gly258Val missense_variant 0.31
embC 4241056 c.1194C>G synonymous_variant 0.23
embC 4241456 p.Ala532Pro missense_variant 0.4
embC 4242476 p.Pro872Ala missense_variant 0.16
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243977 p.Ala249Pro missense_variant 0.38
embA 4244375 c.1143C>G synonymous_variant 0.16
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408329 c.-127C>G upstream_gene_variant 0.16