TB-Profiler result

Run: ERR1200661

Summary

Run ID: ERR1200661

Sample name:

Date: 18-08-2022 14:50:13

Number of reads: 6894198

Percentage reads mapped: 99.4

Strain: lineage4.6.3

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.3 Euro-American T;LAM None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8049 p.Ser250Ala missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 0.99
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781757 c.198C>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
thyA 3073806 c.666C>G synonymous_variant 0.13
embC 4242185 p.Asp775Asn missense_variant 1.0
embC 4242822 p.Val987Gly missense_variant 0.35