TB-Profiler result

Run: ERR1465890

Summary

Run ID: ERR1465890

Sample name:

Date: 31-03-2023 14:28:21

Number of reads: 7249856

Percentage reads mapped: 99.52

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6463 c.-839C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154980 c.1132C>T synonymous_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.25
PPE35 2170066 p.Ala183Thr missense_variant 0.11
PPE35 2170811 c.-199C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3065525 p.His223Tyr missense_variant 1.0
thyX 3067976 c.-31T>C upstream_gene_variant 1.0
thyA 3073806 c.666C>G synonymous_variant 0.28
fbiB 3642615 p.Pro361Ala missense_variant 1.0
embC 4242425 p.Arg855Gly missense_variant 0.19
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247578 c.1065G>A synonymous_variant 1.0
aftB 4268076 p.Met254Ala missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0