TB-Profiler result

Run: ERR161113
Summary

Run ID: ERR161113

Sample name:

Date: 31-03-2023 14:46:35

Number of reads: 3064565

Percentage reads mapped: 92.82

Strain: lineage4.8

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gid 4408100 c.102delG frameshift_variant 1.0 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472708 n.863T>A non_coding_transcript_exon_variant 0.15
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.26
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.26
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.22
rrs 1472786 n.941C>T non_coding_transcript_exon_variant 0.23
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.21
rrs 1472803 n.958T>C non_coding_transcript_exon_variant 0.16
rrs 1473161 n.1316A>C non_coding_transcript_exon_variant 0.1
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.1
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.16
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.13
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.13
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.13
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.13
rrs 1473262 n.1417T>A non_coding_transcript_exon_variant 0.12
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.28
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.29
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.3
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.33
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.34
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.34
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.32
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.32
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.35
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.37
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.36
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.36
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.47
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.45
rrl 1476353 n.2696G>A non_coding_transcript_exon_variant 0.44
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.41
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 0.4
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.42
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.41
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.48
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.48
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.42
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.41
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.27
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.29
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.29
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.29
rrl 1476565 n.2908G>A non_coding_transcript_exon_variant 0.19
rrl 1476566 n.2909A>G non_coding_transcript_exon_variant 0.19
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.19
rrl 1476577 n.2920T>A non_coding_transcript_exon_variant 0.18
rrl 1476578 n.2921C>A non_coding_transcript_exon_variant 0.19
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.18
rrl 1476592 n.2935G>A non_coding_transcript_exon_variant 0.16
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.17
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.16
rrl 1476605 n.2948C>T non_coding_transcript_exon_variant 0.15
rrl 1476608 n.2951C>A non_coding_transcript_exon_variant 0.15
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 0.15
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.15
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.14
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.14
rrl 1476637 n.2980C>A non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747263 c.336C>A synonymous_variant 0.19
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
clpC1 4039729 p.Asp326Asn missense_variant 0.99
embC 4239842 c.-21C>A upstream_gene_variant 0.24
embC 4242422 p.Trp854Gly missense_variant 0.17
embC 4242425 p.Arg855Gly missense_variant 0.28
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0