TB-Profiler result

Run: ERR1633794
Summary

Run ID: ERR1633794

Sample name:

Date: 18-08-2022 14:45:45

Number of reads: 1514750

Percentage reads mapped: 99.52

Strain: lineage4.1.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 0.99
lineage4.1.1.1 Euro-American (X-type) X2 RD183 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5479 c.240C>T synonymous_variant 0.17
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472719 n.874G>T non_coding_transcript_exon_variant 0.14
rrl 1475766 n.2109G>A non_coding_transcript_exon_variant 0.15
fabG1 1673232 c.-208C>T upstream_gene_variant 0.15
fabG1 1673611 p.Val58Leu missense_variant 0.17
inhA 1674952 p.Pro251Ala missense_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2153933 p.Ala727Ser missense_variant 0.25
kasA 2519119 c.1005G>T synonymous_variant 0.15
eis 2714352 c.981C>G synonymous_variant 0.15
ahpC 2726210 c.18T>C synonymous_variant 0.94
ahpC 2726738 c.546C>T synonymous_variant 0.12
folC 2746509 p.Gln364Lys missense_variant 0.17
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiA 3641447 p.Thr302Met missense_variant 0.96
alr 3841006 p.Asp139Asn missense_variant 1.0
embC 4240897 c.1035C>G synonymous_variant 0.9
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0