TB-Profiler result

Run: ERR1633826
Summary

Run ID: ERR1633826

Sample name:

Date: 18-08-2022 14:48:09

Number of reads: 2530064

Percentage reads mapped: 99.69

Strain: lineage4.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.99
lineage4.1.2 Euro-American T;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5182 c.-58C>A upstream_gene_variant 0.15
gyrB 5934 p.Ser232Leu missense_variant 0.2
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 765508 c.2139C>A synonymous_variant 0.13
rpoC 765733 c.2364G>A synonymous_variant 0.14
rpoC 765742 c.2373G>A synonymous_variant 0.12
mmpR5 778813 c.-177G>A upstream_gene_variant 0.23
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800675 c.-134G>A upstream_gene_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673249 c.-191C>T upstream_gene_variant 1.0
inhA 1674952 p.Pro251Ala missense_variant 0.19
tlyA 1917972 c.33A>G synonymous_variant 1.0
folC 2747022 p.Val193Ile missense_variant 1.0
thyA 3073806 c.666C>G synonymous_variant 0.18
fbiA 3641164 p.Ile208Val missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0