TB-Profiler result

Run: ERR1633901
Summary

Run ID: ERR1633901

Sample name:

Date: 18-08-2022 14:49:08

Number of reads: 728878

Percentage reads mapped: 98.96

Strain: lineage2.2.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.98
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.97
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.98
lineage2.2.1.1 East-Asian (Beijing) Beijing-RD150 RD105;RD207;RD181;RD150 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7538 p.Glu79Asp missense_variant 0.15
gyrA 7544 p.Met81Ile missense_variant 0.17
gyrA 7546 p.Gly82Ala missense_variant 0.17
gyrA 7554 p.His85Asn missense_variant 0.18
gyrA 7562 c.261C>T synonymous_variant 0.17
embR 1416379 c.969C>T synonymous_variant 0.2
rrl 1476779 n.3122G>A non_coding_transcript_exon_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
pncA 2289722 c.-481G>A upstream_gene_variant 0.2
eis 2714846 p.Val163Ile missense_variant 0.9
ald 3086788 c.-32T>C upstream_gene_variant 0.91
alr 3841497 c.-77C>A upstream_gene_variant 0.2
embA 4245420 c.2188C>T synonymous_variant 0.15
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0