TB-Profiler result

Run: ERR1750888
Summary

Run ID: ERR1750888

Sample name:

Date: 31-03-2023 14:58:34

Number of reads: 4422249

Percentage reads mapped: 98.67

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.18
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.29
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.29
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.29
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.15
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.2
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.13
rrs 1473115 n.1270G>A non_coding_transcript_exon_variant 0.15
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.17
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.33
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.33
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.33
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.33
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.33
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.4
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.4
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.4
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.38
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.38
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.38
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.38
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.33
rrl 1475278 n.1621G>T non_coding_transcript_exon_variant 0.5
rrl 1475444 n.1787G>A non_coding_transcript_exon_variant 0.5
rrl 1475454 n.1797G>A non_coding_transcript_exon_variant 0.5
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.17
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.18
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.18
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.18
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.22
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.2
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 0.98
clpC1 4039729 p.Asp326Asn missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0