TB-Profiler result

Run: ERR1750920
Summary

Run ID: ERR1750920

Sample name:

Date: 31-03-2023 14:59:59

Number of reads: 2582073

Percentage reads mapped: 96.0

Strain: lineage4.4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.1 Euro-American (S-type) S;T None 1.0
lineage4.4.1.1 Euro-American S;Orphans None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9138 p.Gln613Glu missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777416 c.1065G>T synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471848 n.3T>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.67
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.5
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.33
rrs 1472256 n.411T>C non_coding_transcript_exon_variant 0.25
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.2
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.29
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.33
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.25
rrs 1472680 n.835C>T non_coding_transcript_exon_variant 0.22
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.33
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.33
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 0.18
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.18
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.23
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.14
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.12
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.12
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.18
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.19
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.19
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.18
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.17
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.18
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.18
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.19
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.18
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.2
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.2
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.2
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.2
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.3
rrl 1473582 n.-76T>A upstream_gene_variant 1.0
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.33
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.29
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.29
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.33
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.29
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.29
rrl 1473934 n.277G>A non_coding_transcript_exon_variant 0.25
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.25
rrl 1473936 n.279A>G non_coding_transcript_exon_variant 0.25
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.2
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.2
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.2
rrl 1473964 n.307T>C non_coding_transcript_exon_variant 0.17
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.4
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.4
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.4
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.25
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.25
rrl 1474353 n.696A>C non_coding_transcript_exon_variant 0.25
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.25
rrl 1474355 n.698A>C non_coding_transcript_exon_variant 0.25
rrl 1474356 n.699T>G non_coding_transcript_exon_variant 0.22
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.22
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.25
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.33
rrl 1474488 n.831G>C non_coding_transcript_exon_variant 0.4
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.4
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.4
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.6
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.6
rrl 1474516 n.859C>G non_coding_transcript_exon_variant 0.6
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.43
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.33
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.67
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.67
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.75
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.67
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.67
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1475493 n.1836G>A non_coding_transcript_exon_variant 0.4
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.38
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.5
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.18
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.13
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.13
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.13
rrl 1476015 n.2358G>A non_coding_transcript_exon_variant 0.25
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.25
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.29
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.4
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.33
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.4
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.4
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.4
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.18
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.18
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.18
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.2
rrl 1476443 n.2786G>C non_coding_transcript_exon_variant 0.2
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.43
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.25
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.18
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.2
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.2
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2168479 p.Thr712Pro missense_variant 1.0
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568779 c.-100T>C upstream_gene_variant 1.0
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0