TB-Profiler result

Run: ERR176625
Summary

Run ID: ERR176625

Sample name:

Date: 31-03-2023 15:07:47

Number of reads: 2531262

Percentage reads mapped: 98.76

Strain: lineage4.9.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
lineage4.9.1 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8978 c.1677C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.26
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223145 p.Arg7Lys missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289138 p.Leu35Arg missense_variant 1.0
pncA 2289448 c.-207G>A upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.29
ahpC 2726341 p.Val50Gly missense_variant 0.34
Rv2752c 3067191 c.-1000G>A upstream_gene_variant 1.0
fbiD 3339273 c.156T>G synonymous_variant 0.29
fbiD 3339385 p.Asp90Asn missense_variant 0.98
fbiB 3642772 p.Asp413Ala missense_variant 0.28
rpoA 3878626 c.-119A>C upstream_gene_variant 0.17
rpoA 3878630 c.-123G>C upstream_gene_variant 0.2
rpoA 3878641 c.-134C>G upstream_gene_variant 0.19
clpC1 4038857 c.1848C>A synonymous_variant 0.29
embC 4239842 c.-21C>A upstream_gene_variant 0.27
embC 4242425 p.Arg855Gly missense_variant 0.23
whiB6 4338595 c.-75delG upstream_gene_variant 1.0