TB-Profiler result

Run: ERR1949986
Summary

Run ID: ERR1949986

Sample name:

Date: 31-03-2023 15:36:38

Number of reads: 917341

Percentage reads mapped: 99.65

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 620155 p.Gly89Trp missense_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303158 c.231delG frameshift_variant 0.11
fbiC 1303747 p.Thr273Ala missense_variant 1.0
Rv1258c 1406363 c.978A>G synonymous_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169029 p.Asp528Glu missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746634 p.Asp322Ala missense_variant 0.5
Rv2752c 3064566 c.1626G>C synonymous_variant 0.25
ald 3086987 p.Gln56His missense_variant 0.14
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fprA 3475171 p.Ala389Ser missense_variant 0.11
fbiB 3641832 p.Gly100Arg missense_variant 0.11
fbiB 3642651 p.Phe373Ile missense_variant 0.11
fbiB 3642655 p.Thr374Met missense_variant 0.1
alr 3841114 p.Asp103His missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244467 p.Ile412Thr missense_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408427 c.-225G>A upstream_gene_variant 0.11
Rv3083 3448500 c.-3_*1408del transcript_ablation 1.0