TB-Profiler result

Run: ERR2179691
Summary

Run ID: ERR2179691

Sample name:

Date: 10-08-2022 17:56:19

Number of reads: 2785313

Percentage reads mapped: 98.98

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 0.98
rpoC 765212 p.Pro615Thr missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303106 p.Cys59Phe missense_variant 0.13
Rv1258c 1407380 c.-40C>T upstream_gene_variant 0.93
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.09
inhA 1673586 c.-616C>A upstream_gene_variant 0.94
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170057 p.Val186Met missense_variant 0.12
PPE35 2170568 p.Ile15Met missense_variant 0.97
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339480 p.Gln121His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3641236 p.Ala232Ser missense_variant 0.13
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
clpC1 4038318 p.Pro796Leu missense_variant 0.96
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243482 p.Ala84Ser missense_variant 0.91
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408054 p.Leu50Arg missense_variant 0.94