Run ID: ERR2179767
Sample name:
Date: 19-10-2023 21:48:54
Number of reads: NA
Percentage reads mapped: NA
Strain: lineage4.5
Drug-resistance: RR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.5 | Euro-American | H;T | RD122 | 0.98 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761139 | p.His445Tyr | missense_variant | 0.19 | rifampicin |
rpoB | 761155 | p.Ser450Phe | missense_variant | 0.74 | rifampicin |
rpoB | 761244 | p.Ile480Val | missense_variant | 0.21 | rifampicin |
tlyA | 1918003 | p.Gln22* | stop_gained | 1.0 | capreomycin |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrB | 5247 | p.Ala3Val | missense_variant | 0.99 |
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 7892 | c.591G>A | synonymous_variant | 0.97 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
ccsA | 620029 | c.139C>T | synonymous_variant | 0.92 |
rpoB | 762736 | p.Ala977Val | missense_variant | 1.0 |
rpoB | 762804 | p.Gly1000Ser | missense_variant | 0.2 |
mmpL5 | 775637 | p.Ile948Val | missense_variant | 0.98 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
fbiC | 1302825 | c.-106C>T | upstream_gene_variant | 1.0 |
Rv1258c | 1406101 | p.Pro414Ser | missense_variant | 0.98 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
PPE35 | 2170568 | p.Ile15Met | missense_variant | 1.0 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
rpoA | 3878575 | c.-68C>T | upstream_gene_variant | 0.99 |
clpC1 | 4038318 | p.Pro796Leu | missense_variant | 0.95 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
ethA | 4328382 | c.-909C>T | upstream_gene_variant | 0.95 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |