TB-Profiler result

Run: ERR2228824
Summary

Run ID: ERR2228824

Sample name:

Date: 31-03-2023 16:22:05

Number of reads: 997122

Percentage reads mapped: 99.39

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7451 c.150C>G synonymous_variant 0.11
mshA 576488 p.Val381His missense_variant 0.15
ccsA 620121 c.231G>T synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101854 c.1189C>T synonymous_variant 0.11
PPE35 2168728 p.Gly629Arg missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714866 p.Gly156Val missense_variant 0.13
eis 2714870 p.Gly155Cys missense_variant 0.13
eis 2714872 p.Pro154Arg missense_variant 0.13
eis 2714874 c.459A>C synonymous_variant 0.13
eis 2714878 p.Asp152Ala missense_variant 0.13
folC 2746706 p.Gln298Pro missense_variant 0.11
pepQ 2860107 c.312G>C synonymous_variant 0.11
Rv3236c 3612210 p.Ala303Thr missense_variant 0.1
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244603 c.1371G>T synonymous_variant 0.12
embB 4245581 c.-933C>T upstream_gene_variant 0.12
aftB 4268648 p.Trp63* stop_gained 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0