TB-Profiler result

Run: ERR2229759
Summary

Run ID: ERR2229759

Sample name:

Date: 31-03-2023 17:33:17

Number of reads: 1004711

Percentage reads mapped: 98.03

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491476 p.Lys232Glu missense_variant 0.11
rpoB 759620 c.-187A>C upstream_gene_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
embR 1417065 p.Ala95Thr missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673380 c.-60C>G upstream_gene_variant 0.28
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169191 c.1422G>C synonymous_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726375 c.183C>T synonymous_variant 0.1
folC 2746564 c.1035A>T synonymous_variant 0.15
folC 2746568 c.1030_1031insT frameshift_variant 0.14
thyX 3067350 p.Arg199Gln missense_variant 0.15
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fprA 3475049 p.Ile348Asn missense_variant 0.1
whiB7 3568780 c.-101A>G upstream_gene_variant 0.11
clpC1 4040249 p.Glu152Gly missense_variant 0.1
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243378 p.Ser49Thr missense_variant 0.12
embA 4244498 c.1266A>G synonymous_variant 0.13
embB 4246544 p.Thr11Pro missense_variant 0.1
embB 4246563 p.Leu17Trp missense_variant 0.1
embB 4249751 c.3238T>C synonymous_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448497 c.-6_*1408del transcript_ablation 1.0