TB-Profiler result

Run: ERR2486981
Summary

Run ID: ERR2486981

Sample name:

Date: 15-08-2022 11:00:41

Number of reads: 350489

Percentage reads mapped: 96.82

Strain: lineage4.3.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.2 Euro-American (LAM) LAM3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575920 c.573C>A synonymous_variant 0.15
rpoC 764238 p.Leu290Arg missense_variant 0.22
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 776073 p.Val803Ala missense_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800982 c.174C>T synonymous_variant 0.13
atpE 1461123 p.Gly27Ser missense_variant 0.2
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 1.0
katG 2155890 c.222C>T synonymous_variant 0.2
katG 2156078 p.Thr12Ser missense_variant 0.11
katG 2156280 c.-169T>C upstream_gene_variant 0.11
folC 2747782 c.-184A>C upstream_gene_variant 0.14
ribD 2986827 c.-12G>A upstream_gene_variant 0.2
Rv2752c 3065007 c.1185G>T synonymous_variant 0.12
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3236c 3612626 p.Ala164Asp missense_variant 0.12
fbiB 3641762 p.Lys76Asn missense_variant 0.12
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embC 4240151 p.Ser97Thr missense_variant 0.18
embB 4246807 c.294G>A synonymous_variant 0.17
aftB 4268381 p.Trp152* stop_gained 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0