TB-Profiler result

Run: ERR2503426
Summary

Run ID: ERR2503426

Sample name:

Date: 31-03-2023 18:27:13

Number of reads: 338552

Percentage reads mapped: 99.58

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8011 p.Ser237Phe missense_variant 0.11
gyrA 8661 p.Asp454Asn missense_variant 0.12
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491084 p.Val101Ala missense_variant 0.12
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
ccsA 620521 p.Ala211Thr missense_variant 0.14
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304826 c.1900delT frameshift_variant 0.14
Rv1258c 1406183 c.1158C>T synonymous_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167820 c.2793G>A synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
kasA 2518425 p.Asp104Ala missense_variant 0.15
kasA 2518811 p.Asp233Tyr missense_variant 0.18
eis 2714708 c.624delC frameshift_variant 0.1
pepQ 2860419 c.-1C>T upstream_gene_variant 0.12
ribD 2986827 c.-12G>A upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339565 p.Val150Ile missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612505 p.His204Gln missense_variant 0.22
alr 3840225 p.Thr399Asn missense_variant 1.0
alr 3841038 p.Val128Gly missense_variant 0.11
clpC1 4040559 p.Leu49Gln missense_variant 0.11
embC 4240558 c.696C>T synonymous_variant 0.14
embC 4240674 p.Gly271Val missense_variant 0.17
embC 4241753 p.Ala631Thr missense_variant 0.25
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4248965 p.Pro818Thr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0