TB-Profiler result

Run: ERR2513758
Summary

Run ID: ERR2513758

Sample name:

Date: 31-03-2023 19:53:09

Number of reads: 665550

Percentage reads mapped: 98.78

Strain: lineage4.3.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.1 Euro-American (LAM) LAM9 None 1.0
lineage4.3.1.1 Euro-American (LAM) LAM9 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777605 c.876C>T synonymous_variant 0.1
mmpR5 779455 c.467dupG frameshift_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304084 p.Gly385Val missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471660 n.-186G>A upstream_gene_variant 1.0
rrl 1476350 n.2693G>T non_coding_transcript_exon_variant 0.2
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 0.22
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 0.22
fabG1 1673900 p.Ala154Val missense_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155559 p.Phe185Leu missense_variant 0.17
PPE35 2167965 p.Ala883Gly missense_variant 0.11
PPE35 2167967 c.2646A>C synonymous_variant 0.11
PPE35 2169269 c.1344A>G synonymous_variant 0.12
PPE35 2169272 c.1341C>G synonymous_variant 0.12
PPE35 2169278 c.1335T>C synonymous_variant 0.13
PPE35 2169281 c.1332T>G synonymous_variant 0.12
PPE35 2169293 c.1320T>C synonymous_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714881 p.Ala151Val missense_variant 0.14
pepQ 2860509 c.-91G>A upstream_gene_variant 0.11
Rv2752c 3064666 p.Arg509His missense_variant 0.1
thyX 3067966 c.-21G>A upstream_gene_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339673 p.Arg186Cys missense_variant 0.14
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3640702 p.His54Tyr missense_variant 0.11
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248731 p.Val740Met missense_variant 0.12
aftB 4268768 c.69A>G synonymous_variant 0.15
ubiA 4269046 p.Ala263Val missense_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0