TB-Profiler result

Run: ERR2513971
Summary

Run ID: ERR2513971

Sample name:

Date: 31-03-2023 20:01:48

Number of reads: 736278

Percentage reads mapped: 99.6

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7539 p.Thr80Pro missense_variant 0.12
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9286 p.Ala662Val missense_variant 0.18
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.24
ccsA 620020 p.Leu44Val missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoB 759620 c.-187A>C upstream_gene_variant 0.29
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 778037 c.-953G>A upstream_gene_variant 0.12
mmpS5 778737 c.167_168delTG frameshift_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406101 p.Pro414Ser missense_variant 1.0
atpE 1461210 p.Thr56Ser missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471735 n.-111T>C upstream_gene_variant 0.11
fabG1 1673357 c.-83G>A upstream_gene_variant 0.11
fabG1 1673359 c.-81T>C upstream_gene_variant 0.19
fabG1 1673361 c.-79C>G upstream_gene_variant 0.12
fabG1 1673380 c.-60C>G upstream_gene_variant 0.12
rpsA 1834826 p.Thr429Ala missense_variant 0.12
rpsA 1834946 p.Gln469Glu missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169354 p.Gly420Val missense_variant 0.12
PPE35 2170285 p.Val110Leu missense_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2222013 c.1152C>T synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289840 c.-599C>G upstream_gene_variant 0.2
pncA 2290026 c.-785C>T upstream_gene_variant 0.14
pncA 2290048 c.-807C>T upstream_gene_variant 0.12
kasA 2518683 p.Ala190Val missense_variant 0.14
kasA 2518686 p.Asp191Gly missense_variant 0.15
kasA 2518694 p.Val194Leu missense_variant 0.15
ahpC 2726341 p.Val50Gly missense_variant 0.33
folC 2746745 p.Val285Gly missense_variant 0.13
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243392 p.Asn54Asp missense_variant 0.11
ethA 4326218 p.Val419Ala missense_variant 0.12
ethA 4326604 p.Asp290Glu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0