TB-Profiler result

Run: ERR2514495
Summary

Run ID: ERR2514495

Sample name:

Date: 31-03-2023 20:22:23

Number of reads: 915976

Percentage reads mapped: 99.66

Strain: lineage4.3.4.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.1 Euro-American (LAM) LAM1;LAM2 RD174 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491576 p.Pro265Gln missense_variant 0.13
rpoB 763191 p.Val1129Ile missense_variant 0.11
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 766260 c.2893delG frameshift_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775802 p.Met893Ile missense_variant 0.11
mmpL5 778099 p.Asp128Tyr missense_variant 0.13
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2222854 p.Ile104Thr missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518141 c.29dupG frameshift_variant 0.43
kasA 2518177 c.63G>T synonymous_variant 0.17
eis 2715076 p.Ala86Glu missense_variant 0.11
ribD 2986674 c.-165G>T upstream_gene_variant 0.11
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339145 p.Ile10Phe missense_variant 0.12
fbiD 3339273 c.156T>G synonymous_variant 0.22
fbiD 3339757 p.Arg214Gly missense_variant 0.11
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4039361 c.1344C>A synonymous_variant 0.11
clpC1 4039991 c.714G>A synonymous_variant 1.0
panD 4044302 c.-21C>A upstream_gene_variant 0.13
embC 4242596 p.Gly912Cys missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244292 p.Leu354Met missense_variant 0.2
aftB 4267585 p.Thr418Ala missense_variant 0.1
aftB 4268684 c.153G>A synonymous_variant 0.1
ubiA 4270011 c.-178A>G upstream_gene_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0