TB-Profiler result

Run: ERR2514551
Summary

Run ID: ERR2514551

Sample name:

Date: 31-03-2023 20:24:31

Number of reads: 1126867

Percentage reads mapped: 99.49

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575877 p.Ala177Val missense_variant 0.11
mshA 576751 p.Lys468Asn missense_variant 0.17
rpoB 759615 c.-192A>C upstream_gene_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302885 c.-46G>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746328 p.Arg424Leu missense_variant 0.11
Rv2752c 3064875 c.1317C>G synonymous_variant 1.0
ald 3086987 p.Gln56His missense_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fprA 3474119 p.Met38Thr missense_variant 1.0
Rv3236c 3612445 c.672C>T synonymous_variant 0.12
fbiA 3641477 p.Asp312Gly missense_variant 1.0
embC 4240655 p.Ala265Pro missense_variant 0.12
embC 4241586 p.Ser575Tyr missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267908 p.Ala310Asp missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448508 c.6_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0