TB-Profiler result

Run: ERR2514613
Summary

Run ID: ERR2514613

Sample name:

Date: 31-03-2023 20:27:23

Number of reads: 3936824

Percentage reads mapped: 98.98

Strain: lineage4.8

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.15 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472135 n.290C>G non_coding_transcript_exon_variant 0.11
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.14
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.21
rrs 1472431 n.586G>A non_coding_transcript_exon_variant 0.2
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.2
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.2
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.2
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.27
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.27
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.27
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.33
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.36
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.36
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.36
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.18
rrs 1472504 n.659A>T non_coding_transcript_exon_variant 0.18
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.17
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.23
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.23
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.23
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.23
rrs 1472574 n.729T>A non_coding_transcript_exon_variant 0.23
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.23
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.17
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.18
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.18
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.15
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.15
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475877 n.2220C>G non_coding_transcript_exon_variant 0.22
rrl 1475878 n.2221T>A non_coding_transcript_exon_variant 0.22
rrl 1475879 n.2222T>C non_coding_transcript_exon_variant 0.22
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.2
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.2
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.2
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.15
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.15
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.18
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.18
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
clpC1 4039729 p.Asp326Asn missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448497 c.-6_*1408del transcript_ablation 1.0