TB-Profiler result

Run: ERR2514767
Summary

Run ID: ERR2514767

Sample name:

Date: 31-03-2023 20:32:56

Number of reads: 374055

Percentage reads mapped: 98.99

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 490650 c.-133G>A upstream_gene_variant 0.11
fgd1 490751 c.-32T>G upstream_gene_variant 0.2
fgd1 491027 p.Asn82Thr missense_variant 0.13
mshA 575891 p.Ala182Thr missense_variant 1.0
mshA 576123 p.Leu259Arg missense_variant 0.13
mshA 576751 p.Lys468Asn missense_variant 0.4
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471888 n.43C>A non_coding_transcript_exon_variant 0.2
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518814 p.Arg234Cys missense_variant 0.22
eis 2715057 c.276C>T synonymous_variant 0.25
eis 2715432 c.-100C>T upstream_gene_variant 0.12
eis 2715436 c.-104G>A upstream_gene_variant 0.12
eis 2715440 c.-108A>C upstream_gene_variant 0.12
eis 2715445 c.-113C>T upstream_gene_variant 0.12
eis 2715447 c.-115T>A upstream_gene_variant 0.12
eis 2715450 c.-118T>C upstream_gene_variant 0.12
eis 2715451 c.-119C>A upstream_gene_variant 0.12
eis 2715454 c.-122T>G upstream_gene_variant 0.12
eis 2715455 c.-123G>A upstream_gene_variant 0.12
eis 2715458 c.-126T>A upstream_gene_variant 0.12
eis 2715460 c.-128A>G upstream_gene_variant 0.12
eis 2715465 c.-133G>T upstream_gene_variant 0.14
eis 2715469 c.-137T>C upstream_gene_variant 0.25
eis 2715473 c.-141A>G upstream_gene_variant 0.2
ahpC 2726338 p.Val49Gly missense_variant 0.25
Rv2752c 3064909 p.Ser428Asn missense_variant 0.17
thyA 3074645 c.-174T>G upstream_gene_variant 0.5
fbiD 3339273 c.156T>G synonymous_variant 0.3
fbiB 3640782 c.-753C>G upstream_gene_variant 0.17
fbiB 3642484 p.Trp317Ser missense_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242928 c.-305A>G upstream_gene_variant 1.0
embB 4247595 p.Cys361Ser missense_variant 1.0
aftB 4268040 p.Leu266Pro missense_variant 1.0
aftB 4268840 c.-4G>A upstream_gene_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0