Run ID: ERR257885
Sample name:
Date: 31-03-2023 22:22:01
Number of reads: 557782
Percentage reads mapped: 98.86
Strain: lineage4
Drug-resistance: HR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
fabG1 | 1673425 | c.-15C>T | upstream_gene_variant | 1.0 | isoniazid, ethionamide |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 8888 | c.1587C>A | synonymous_variant | 0.15 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
fgd1 | 491270 | p.Tyr163Cys | missense_variant | 1.0 |
rpoB | 762824 | p.Asp1006Glu | missense_variant | 0.12 |
rpoC | 764692 | c.1323C>T | synonymous_variant | 0.25 |
rpoC | 765938 | p.Arg857* | stop_gained | 0.12 |
rpoC | 767314 | p.Tyr1315* | stop_gained | 0.29 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
Rv1258c | 1406319 | p.Ala341Gly | missense_variant | 0.12 |
Rv1258c | 1406929 | p.Ser138Ala | missense_variant | 0.22 |
embR | 1417526 | c.-179G>T | upstream_gene_variant | 0.1 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrl | 1474571 | n.914G>A | non_coding_transcript_exon_variant | 1.0 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
katG | 2154915 | c.1197A>G | synonymous_variant | 1.0 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
folC | 2746460 | p.Ser380Thr | missense_variant | 0.11 |
Rv2752c | 3065722 | p.Ala157Glu | missense_variant | 0.11 |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
whiB7 | 3568821 | c.-142A>G | upstream_gene_variant | 0.15 |
Rv3236c | 3612169 | c.947delA | frameshift_variant | 0.18 |
clpC1 | 4040327 | p.Lys126Asn | missense_variant | 0.25 |
embC | 4242357 | c.2497_2499dupAAC | conservative_inframe_insertion | 1.0 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
embB | 4248645 | p.Ala711Val | missense_variant | 0.2 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |