TB-Profiler result

Run: ERR2652931
Summary

Run ID: ERR2652931

Sample name:

Date: 31-03-2023 22:24:20

Number of reads: 1046235

Percentage reads mapped: 99.71

Strain: lineage4.4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.1 Euro-American (S-type) S;T None 1.0
lineage4.4.1.1 Euro-American S;Orphans None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 759852 p.Ser16Gly missense_variant 0.1
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305056 p.Met709Lys missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2169840 p.Gly258Asp missense_variant 0.97
PPE35 2170031 c.581delG frameshift_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715510 c.-178G>T upstream_gene_variant 1.0
Rv2752c 3067058 c.-867T>C upstream_gene_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568635 p.Leu15Phe missense_variant 0.11
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
fbiB 3642090 p.Glu186* stop_gained 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267867 p.Leu324Met missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0