TB-Profiler result

Run: ERR270632
Summary

Run ID: ERR270632

Sample name:

Date: 31-03-2023 23:06:06

Number of reads: 4134699

Percentage reads mapped: 99.58

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 0.99
mmpL5 775639 p.Ile948Val missense_variant 0.99
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416411 c.937C>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.99
inhA 1674952 p.Pro251Ala missense_variant 0.24
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339603 c.486C>T synonymous_variant 0.16
Rv3083 3448497 c.-7T>A upstream_gene_variant 0.8
Rv3083 3448500 c.-4A>G upstream_gene_variant 0.67
Rv3083 3448501 c.-3G>T upstream_gene_variant 0.67
Rv3083 3449875 p.His458Tyr missense_variant 1.0
rpoA 3878569 c.-62C>G upstream_gene_variant 0.14
rpoA 3878574 c.-67G>C upstream_gene_variant 0.13
clpC1 4038857 c.1848C>A synonymous_variant 0.27
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0