TB-Profiler result

Run: ERR270675
Summary

Run ID: ERR270675

Sample name:

Date: 31-03-2023 23:08:11

Number of reads: 4326337

Percentage reads mapped: 99.7

Strain: lineage4.9

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
katG 2155168 p.Ser315Thr missense_variant 0.96 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 0.99
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860153 p.Glu89Gly missense_variant 0.12
thyA 3073806 c.666C>G synonymous_variant 0.24
embC 4239842 c.-21C>A upstream_gene_variant 0.25
embC 4242425 p.Arg855Gly missense_variant 0.21
whiB6 4338497 p.Ala9Ser missense_variant 0.97
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407991 p.Gly71Glu missense_variant 1.0