TB-Profiler result

Run: ERR279477
Summary

Run ID: ERR279477

Sample name:

Date: 31-03-2023 23:37:46

Number of reads: 4094533

Percentage reads mapped: 94.44

Strain: lineage4.4.1.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 0.99
lineage4.4.1 Euro-American (S-type) S;T None 0.99
lineage4.4.1.1 Euro-American S;Orphans None 1.0
lineage4.4.1.1.1 Euro-American S;Orphans None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.19
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.19
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.25
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.27
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.27
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.44
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.42
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.4
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.4
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.43
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.33
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.29
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.25
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.38
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 0.5
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.5
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.5
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.43
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.4
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.4
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.4
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.25
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.25
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.25
rrs 1472779 n.934G>A non_coding_transcript_exon_variant 0.25
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.25
rrs 1472786 n.941C>T non_coding_transcript_exon_variant 0.25
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.22
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.22
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.5
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.5
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.5
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.5
rrs 1473070 n.1225G>A non_coding_transcript_exon_variant 0.5
rrs 1473094 n.1249T>A non_coding_transcript_exon_variant 0.57
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.57
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.33
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.33
rrs 1473115 n.1270G>C non_coding_transcript_exon_variant 0.33
rrs 1473123 n.1278A>C non_coding_transcript_exon_variant 0.29
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.33
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.4
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.44
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.55
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.73
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.7
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.73
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.8
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.8
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 0.75
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.75
rrl 1474927 n.1271delC non_coding_transcript_exon_variant 0.6
rrl 1474931 n.1274G>A non_coding_transcript_exon_variant 0.6
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 0.5
rrl 1475849 n.2192G>A non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.33
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.5
rrl 1476378 n.2721C>T non_coding_transcript_exon_variant 0.22
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.62
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.62
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.62
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.67
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.67
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.67
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.5
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.5
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.5
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.33
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.29
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.25
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 0.22
rrl 1476621 n.2964C>A non_coding_transcript_exon_variant 0.2
rrl 1476624 n.2967T>G non_coding_transcript_exon_variant 0.2
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.2
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.2
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.2
rrl 1476637 n.2980C>G non_coding_transcript_exon_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2168066 c.2547C>T synonymous_variant 0.15
PPE35 2169840 p.Gly258Asp missense_variant 0.96
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086762 c.-58C>T upstream_gene_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612665 p.Val151Ala missense_variant 0.99
clpC1 4038857 c.1848C>A synonymous_variant 0.45
embC 4239842 c.-21C>A upstream_gene_variant 0.28
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0