TB-Profiler result

Run: ERR279493
Summary

Run ID: ERR279493

Sample name:

Date: 31-03-2023 23:38:27

Number of reads: 3933849

Percentage reads mapped: 99.53

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.91
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 0.89
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 0.9
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.8
gyrA 9304 p.Gly668Asp missense_variant 0.89
rpoC 765150 p.Gly594Glu missense_variant 0.89
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2221949 p.Ala406Thr missense_variant 0.94
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.33
ald 3086788 c.-32T>C upstream_gene_variant 0.91
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.88
fbiB 3641807 c.273C>G synonymous_variant 0.89
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.9
embB 4249408 c.2895G>A synonymous_variant 0.89
aftB 4267427 c.1410G>A synonymous_variant 0.12
ethR 4327691 p.Asp48Gly missense_variant 0.91
whiB6 4338595 c.-75delG upstream_gene_variant 1.0