TB-Profiler result

Run: ERR3797076
Summary

Run ID: ERR3797076

Sample name:

Date: 2024-10-05T05:52:49.476518

Number of reads: 243127

Percentage reads mapped: 92.17

Median coverage: 7.0

Strain: La1.8.1

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8 M.bovis None 1.0
La1.8.1 M.bovis None 1.0
La1 M.bovis None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rpsA 1834859 p.Ala440Thr missense_variant 1.0 pyrazinamide Uncertain significance
bacA 2063157 c.1572C>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
katG 2155503 c.609C>T synonymous_variant 1.0 isoniazid Not assoc w R
Rv2681 2997325 p.Ala196Val missense_variant 1.0 capreomycin Uncertain significance
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4242642 p.Arg927His missense_variant 1.0 ethambutol Uncertain significance