TB-Profiler result

Run: ERR386784
Summary

Run ID: ERR386784

Sample name:

Date: 01-04-2023 03:28:42

Number of reads: 39746

Percentage reads mapped: 97.55

Strain: lineage4.9

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6098 p.Val287Met missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoC 765297 p.Pro643Leu missense_variant 1.0
rpoC 766324 c.2955C>T synonymous_variant 0.67
rplC 801372 p.Glu188Asp missense_variant 1.0
fbiC 1303556 p.Pro209Leu missense_variant 0.67
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472808 n.963C>T non_coding_transcript_exon_variant 1.0
rpsA 1833717 p.Thr59Ile missense_variant 0.67
rpsA 1833971 c.430C>T synonymous_variant 0.67
katG 2155198 p.Gly305Val missense_variant 0.4
katG 2155216 p.Gly299Asp missense_variant 0.4
PPE35 2169401 c.1212G>A synonymous_variant 1.0
eis 2715299 p.Asp12Asn missense_variant 0.5
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
clpC1 4039998 p.Gly236Ala missense_variant 0.5
embC 4241644 c.1782G>A synonymous_variant 1.0
aftB 4267178 c.1659C>T synonymous_variant 0.67
ethR 4327552 p.Thr2Ala missense_variant 0.67
ethR 4327708 p.Ala54Thr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0