TB-Profiler result

Run: ERR3994094
Summary

Run ID: ERR3994094

Sample name:

Date: 01-04-2023 03:42:15

Number of reads: 2294266

Percentage reads mapped: 99.96

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6847 c.-455C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 766085 p.Pro906Ala missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406153 c.1188G>A synonymous_variant 0.2
atpE 1460992 c.-53A>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471983 n.138C>G non_coding_transcript_exon_variant 0.12
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167818 p.Gly932Val missense_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2986850 c.12T>C synonymous_variant 0.1
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fbiB 3642373 p.Val280Asp missense_variant 0.33
fbiB 3642575 c.1041C>T synonymous_variant 0.12
alr 3840420 p.Arg334Pro missense_variant 0.17
alr 3840455 c.966G>A synonymous_variant 0.11
alr 3840764 c.657G>C synonymous_variant 1.0
clpC1 4038179 c.2522_2525delGCGG frameshift_variant 0.25
embC 4240190 p.Pro110Ser missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242875 p.Glu1005Lys missense_variant 0.12
embA 4242961 c.-272G>A upstream_gene_variant 0.12
embA 4244755 p.Glu508Val missense_variant 0.29
embB 4246766 p.Cys85Arg missense_variant 0.13
embB 4249280 p.Gly923Arg missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0