TB-Profiler result

Run: ERR403358
Summary

Run ID: ERR403358

Sample name:

Date: 01-04-2023 04:26:19

Number of reads: 2188025

Percentage reads mapped: 99.69

Strain: lineage4.6.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.3 Euro-American T;LAM None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8049 p.Ser250Ala missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 0.98
ccsA 620072 p.Pro61Leu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776987 c.1493delC frameshift_variant 1.0
mmpS5 778673 p.Pro78Leu missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674952 p.Pro251Ala missense_variant 0.26
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2153933 p.Ala727Ser missense_variant 0.27
katG 2156437 c.-326C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.25
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878630 c.-123G>C upstream_gene_variant 0.12
rpoA 3878641 c.-134C>G upstream_gene_variant 0.23
clpC1 4038857 c.1848C>A synonymous_variant 0.35
embC 4242185 p.Asp775Asn missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268573 p.Met88Ile missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0