TB-Profiler result

Run: ERR4195539
Summary

Run ID: ERR4195539

Sample name:

Date: 01-04-2023 05:21:30

Number of reads: 3184419

Percentage reads mapped: 99.54

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9030 p.Tyr577His missense_variant 0.11
gyrA 9424 p.Asp708Ala missense_variant 1.0
rpoC 764399 p.Tyr344Asp missense_variant 0.12
rpoC 766813 c.3444G>A synonymous_variant 0.95
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303749 c.819G>T synonymous_variant 1.0
atpE 1460992 c.-53A>C upstream_gene_variant 0.96
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.12
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289890 c.-649C>A upstream_gene_variant 0.12
thyA 3073948 p.Pro175Leu missense_variant 0.13
thyA 3073956 c.516G>T synonymous_variant 0.12
Rv3083 3448497 c.-7T>A upstream_gene_variant 0.33
alr 3840764 c.657G>C synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408342 c.-140C>G upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0