TB-Profiler result

Run: ERR4383947
Summary

Run ID: ERR4383947

Sample name:

Date: 01-04-2023 05:43:20

Number of reads: 617807

Percentage reads mapped: 99.55

Strain: lineage4.3.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.1 Euro-American (LAM) LAM9 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491084 p.Val101Gly missense_variant 0.12
mshA 576108 p.Ala254Gly missense_variant 0.21
ccsA 620434 p.Gly182Ser missense_variant 0.13
rpoC 764159 c.790C>T synonymous_variant 0.11
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416190 c.1158C>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1833445 c.-97A>G upstream_gene_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169467 c.1146C>T synonymous_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2986845 p.Asp3Asn missense_variant 0.11
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878211 c.297G>A synonymous_variant 0.11
rpoA 3878541 c.-34C>T upstream_gene_variant 0.25
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245034 p.Arg601His missense_variant 0.11
embB 4246584 p.Arg24Pro missense_variant 0.5
whiB6 4338467 p.Val19Ile missense_variant 0.12
whiB6 4338525 c.-4G>A upstream_gene_variant 0.12
whiB6 4338538 c.-17T>A upstream_gene_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0