TB-Profiler result

Run: ERR4407536
Summary

Run ID: ERR4407536

Sample name:

Date: 01-04-2023 05:49:02

Number of reads: 1030442

Percentage reads mapped: 97.15

Strain: lineage4.4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.1 Euro-American (S-type) S;T None 1.0
lineage4.4.1.1 Euro-American S;Orphans None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304243 p.Pro438Leu missense_variant 1.0
Rv1258c 1406338 p.Val335Met missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 1.0
rrs 1472571 n.726G>T non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 1.0
rrs 1472582 n.737G>T non_coding_transcript_exon_variant 1.0
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 1.0
rrs 1472585 n.740A>C non_coding_transcript_exon_variant 1.0
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 1.0
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.75
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.5
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.5
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.5
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.5
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.5
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.5
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.38
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.33
rrs 1472767 n.922G>C non_coding_transcript_exon_variant 0.75
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.67
rrs 1472812 n.967A>T non_coding_transcript_exon_variant 0.67
fabG1 1673465 p.Ala9Val missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2169206 c.1407A>G synonymous_variant 0.18
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289845 c.-604G>T upstream_gene_variant 0.17
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568831 c.-152C>A upstream_gene_variant 0.11
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248906 p.Val798Ala missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407800 p.Val135Met missense_variant 0.1