TB-Profiler result

Run: ERR4423501
Summary

Run ID: ERR4423501

Sample name:

Date: 01-04-2023 05:51:23

Number of reads: 1834435

Percentage reads mapped: 99.57

Strain: lineage4.9

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761139 p.His445Asp missense_variant 1.0 rifampicin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6136 c.897G>A synonymous_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474314 n.657G>T non_coding_transcript_exon_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168232 p.Ile794Asn missense_variant 0.11
Rv2752c 3065058 c.1134C>T synonymous_variant 1.0
Rv2752c 3065528 c.664C>T synonymous_variant 1.0
embC 4241644 c.1782G>T synonymous_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0