Run ID: ERR4553475
Sample name:
Date: 01-04-2023 06:11:04
Number of reads: 1584464
Percentage reads mapped: 99.84
Strain: lineage4.9
Drug-resistance: MDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.9 | Euro-American (H37Rv-like) | T1 | None | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761155 | p.Ser450Trp | missense_variant | 1.0 | rifampicin |
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
embB | 4247431 | p.Met306Ile | missense_variant | 1.0 | ethambutol |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
fgd1 | 491377 | p.Gly199Arg | missense_variant | 1.0 |
mshA | 576108 | p.Ala254Gly | missense_variant | 0.27 |
rpoB | 761969 | c.2163G>A | synonymous_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
tlyA | 1918089 | c.150C>G | synonymous_variant | 1.0 |
PPE35 | 2170763 | c.-151C>T | upstream_gene_variant | 1.0 |
embB | 4248851 | c.2338C>T | synonymous_variant | 1.0 |
ethA | 4326977 | p.His166Pro | missense_variant | 1.0 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |