TB-Profiler result

Run: ERR4812668

Summary

Run ID: ERR4812668

Sample name:

Date: 01-04-2023 12:14:12

Number of reads: 329607

Percentage reads mapped: 99.04

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7701 c.400C>T synonymous_variant 0.25
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 763796 p.Met143Val missense_variant 0.17
rpoC 764630 p.Arg421Ser missense_variant 0.25
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781703 c.144G>T synonymous_variant 0.13
Rv1258c 1406179 p.Val388Met missense_variant 1.0
embR 1417230 p.Ala40Thr missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474285 n.628C>A non_coding_transcript_exon_variant 0.29
rrl 1474464 n.807C>T non_coding_transcript_exon_variant 1.0
inhA 1674703 c.502T>C synonymous_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289075 p.Asp56Gly missense_variant 0.12
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612874 c.243G>A synonymous_variant 0.17
fbiA 3640473 c.-70G>T upstream_gene_variant 0.12
clpC1 4040310 p.Thr132Asn missense_variant 0.33
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4248510 p.Ile666Thr missense_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408070 p.Trp45Arg missense_variant 1.0