TB-Profiler result

Run: ERR4814576
Summary

Run ID: ERR4814576

Sample name:

Date: 01-04-2023 13:22:32

Number of reads: 1796714

Percentage reads mapped: 99.31

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 760681 p.Asn292Ser missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.21
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.21
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.2
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.2
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.2
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.21
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.21
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.21
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.23
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.23
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.23
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.25
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.25
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.31
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.13
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.11
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.11
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.15
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.16
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.14
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.14
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474201 n.544T>A non_coding_transcript_exon_variant 0.4
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.27
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.18
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.2
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.2
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.2
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.22
rrl 1474285 n.630_631delTC non_coding_transcript_exon_variant 0.22
rrl 1474294 n.637C>T non_coding_transcript_exon_variant 0.2
rrl 1474295 n.638C>T non_coding_transcript_exon_variant 0.2
rrl 1474296 n.640_651delCTCCGGAGGAGG non_coding_transcript_exon_variant 0.2
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.18
rrl 1474326 n.669T>A non_coding_transcript_exon_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
PPE35 2170400 c.213G>C synonymous_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
clpC1 4039729 p.Asp326Asn missense_variant 0.96
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0