TB-Profiler result

Run: ERR4814787
Summary

Run ID: ERR4814787

Sample name:

Date: 01-04-2023 13:29:37

Number of reads: 4209455

Percentage reads mapped: 90.49

Strain: lineage4.3.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.3 Euro-American (LAM) LAM;T RD115 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.4
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.33
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.25
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.25
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.25
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.29
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.29
rrs 1472973 n.1128A>C non_coding_transcript_exon_variant 0.18
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.18
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.18
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.18
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.18
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.18
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.18
rrs 1472996 n.1151T>C non_coding_transcript_exon_variant 0.2
rrs 1473158 n.1313T>C non_coding_transcript_exon_variant 0.12
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.13
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.12
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.12
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.12
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.11
rrs 1473215 n.1370A>G non_coding_transcript_exon_variant 0.11
rrl 1476406 n.2749T>C non_coding_transcript_exon_variant 0.33
rrl 1476563 n.2906G>A non_coding_transcript_exon_variant 0.33
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.2
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.2
rrl 1476590 n.2933T>C non_coding_transcript_exon_variant 0.2
rrl 1476609 n.2952G>A non_coding_transcript_exon_variant 0.15
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.15
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.15
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.12
rrl 1476629 n.2973dupA non_coding_transcript_exon_variant 0.12
rpsA 1834836 p.Met432Thr missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2156196 c.-85C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 1.0
folC 2746340 p.Ala420Val missense_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0