TB-Profiler result

Run: ERR4814801
Summary

Run ID: ERR4814801

Sample name:

Date: 01-04-2023 13:29:48

Number of reads: 4759460

Percentage reads mapped: 96.13

Strain: lineage4.8

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.65 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6815 p.Lys526Gln missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8138 c.837C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.2
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.27
rrs 1472431 n.586G>A non_coding_transcript_exon_variant 0.4
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.4
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.4
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.33
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.33
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.57
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.56
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.56
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.71
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.75
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.74
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.76
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.59
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.71
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.29
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.79
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.74
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.74
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.74
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.6
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.5
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.5
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.5
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.4
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.5
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.5
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.33
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 0.29
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.33
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.33
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.55
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.55
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.65
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.65
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.73
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.73
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.7
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.25
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.2
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.17
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.24
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.11
rrs 1473285 n.1442_1443delCC non_coding_transcript_exon_variant 0.11
rrs 1473292 n.1447G>T non_coding_transcript_exon_variant 0.14
rrs 1473293 n.1448G>T non_coding_transcript_exon_variant 0.14
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.8
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 0.8
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.6
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.8
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.8
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.8
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.8
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.75
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.13
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.13
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.13
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.13
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.14
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.17
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.18
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.4
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.4
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.5
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.5
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.4
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.22
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.56
rrl 1476523 n.2867delC non_coding_transcript_exon_variant 0.18
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918605 c.666C>T synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714338 p.Lys332Thr missense_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3083 3448500 c.-4A>G upstream_gene_variant 1.0
Rv3083 3448501 c.-3G>T upstream_gene_variant 1.0
alr 3840764 c.657G>C synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0